PUBLICATIONS
Explore peer-reviewed research articles featuring polymer nanodisc technology.
These publications include contributions from our team members through their affiliations with Stellenbosch University (Klumperman Research Group) and international academic partners, reflecting our active role in advancing polymer science for life science applications.
Featured Research: BzAM Terpolymer Series
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Gestél C. Kuyler, Elaine Barnard, Pooja Sridhar, Rebecca J. Murray, Naomi L. Pollock, Mark Wheatley, Timothy R. Dafforn, and Bert Klumperman. Tunable Terpolymer Series for the Systematic Investigation of Membrane Proteins. Biomacromolecules. 2025, 26 (1), 415-427
Gestél C. Kuyler, Elaine Barnard, Randy D. Cunningham, Sinothando Sibariboyi, Luke White, Ilanie Wessels, Michael-Phillip Smith, Bennie Motloung, and Bert Klumperman. Amphiphilic Copolymers and Their Role in the Study of Membrane Proteins. The Journal of Physical Chemistry Letters. 2025, 16 (23), 5784-5799
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Hoor Ayub, Rebecca J. Murray, Gestél C. Kuyler, Farhaan Napier-Khwaja, Joseph Gunner, Tim R. Dafforn, Bert Klumperman, David R. Poyner, and Mark Wheatley. GPCRs in the round: SMA-like copolymers and SMALPs as a platform for investigating GPCRs. Archives of Biochemistry and Biophysics. 2024, Volume 754, 109946.
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Rachael L. Grime, Richard T. Logan, Stephanie A. Nestorow, Pooja Sridhar, Patricia C. Edwards, Christopher G. Tate, Bert Klumperman, Tim R. Dafforn, David R. Poyner, Philip J. Reeves and Mark Wheatley. Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles. Nanoscale. 2021, 13, 13519-13528.
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Lauren E. Ball, Liam J. Riley, Waled Hadasha, Rueben Pfukwa, Corinne J.I. Smith, Timothy R. Dafforn, andBert Klumperman. Influence of DIBMA Polymer Length on Lipid Nanodisc Formation and Membrane Protein Extraction.Biomacromolecules. 2021, 22, 763-772
Randy D. Cunningham, Adrian H. Kopf, Barend O. W. Elenbaas, Bastiaan B.P. Staal, Rueben Pfukwa, J. Antoinette Killian, and Bert Klumperman. Iterative RAFT-Mediated Copolymerization of Styrene and Maleic Anhydride toward Sequence- and Length-Controlled Copolymers and Their Applications for Solubilizing Lipid Membranes. Biomacromolecules. 2020, 21, 3287-3300